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Carotid atherosclerosis was significantly more pronounced in people with WML.The difference in common carotid IMT was 0.13 mm(95%confidence interval[CI]0.04-0.21),whereas the odds ratio of WML associated with plaques in the carotid bifurcation was 3.9.The degree of internal carotid artery stenosis was not,however,associated with WML.The mean ABI was significantly lower in people with WML than in those without lesions with a difference of-0.11(95%CI-0.21 to-0.01).The odds ratio of WML associated with peripheral arterial disease and a possible or definite myocardial infarction was 2.4 and 3.1,respectively.We conclude that atherosclerosis, indicated by increased common carotid IMT,carotid plaques,and a lower ABI, is related to WML. |
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